Long-Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate-Rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair

A platelet lysate-rich plasma macroporous hydrogel scaffold with around 100 μm pore size and 1.25 MPa Young’s modulus was developed to sustainedly recruit and polarize endogenous anti-inflammatory macrophages for improving cartilage defect repair.