monocytes

[Neurobiology of Disease] Current evidence points towards infiltrating monocytes as also playing a role in neuron death. Further characterization of the successive molecular changes in both the resident and peripheral immune cells invading the Parkinson's disease brain will provide targets for disease modification.

[Proceedings of the National Academy of Sciences of the United States of America] 12,13-dihydroxyoctadecenoic acid was found to facilitate the maturation and activation of stimulated neutrophils, while impeding monocyte and macrophage functionality and cytokine generation.

[Infection and Immunity] Investigators compare the fundamental differences between alveolar macrophages and circulating monocyte-derived macrophages in the context of tuberculosis and summarize the recent advances in elucidating the epigenomes of these cells.

[Nature Communications] Scientists showed that in COPD patients, protein arginine methyltransferase 7 (PRMT7) expression was elevated in the lung tissue and localized to the macrophages.

[Pediatric Research] The authors compared immune cell populations, inflammatory and anti-inflammatory cytokine and chemokine levels in the serum, and monocyte and T cell functional activity using umbilical cord samples from neonates with known opioid exposure during gestation and from control neonates without known exposure.

[Science Signaling] In human pulmonary aortic endothelial cells,lipopolysaccharide (LPS) induced decreased in the amounts of endothelial nitric oxide synthase, thrombomodulin, and vascular endothelial–cadherin, which was blocked by treatment with UNC2250.