Tag results:
monocytes
Endothelial Cell News
Emerging Concepts of Vascular Cell Clonal Expansion in Atherosclerosis
[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.
Pancreatic Cell News
The Induction of Peripheral Trained Immunity in the Pancreas Incites Anti-tumor Activity to Control Pancreatic Cancer Progression
[Nature Communications] Scientists demonstrated that yeast-derived particulate β-glucan, an inducer of trained immunity, trafficed to the pancreas, which caused a CCR2-dependent influx of monocytes/macrophages to the pancreas that display features of trained immunity.
Human Immunology News
Single-Cell RNA Sequencing Reveals Induction of Distinct Trained Immunity Programs in Human Monocytes
[Journal of Clinical Investigation] Researchers demonstrated cellular transcriptional programs to four different inducers of trained immunity in monocyte populations at single-cell resolution.
Dermal Cell News
Interplay between Soluble CD74 and Macrophage-Migration Inhibitory Factor Drives Tumor Growth and Influences Patient Survival in Melanoma
[Cell Death & Disease] Scientists assessed the composition and production mechanisms, as well as the clinical significance and biological properties, of soluble CD74 in melanoma.
Mesenchymal Cell News
Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells
[Clinical Cancer Research] Researchers characterized changes in the soft tissue sarcoma tumor immune microenvironment induced by standard neoadjuvant therapy with the goal of informing neoadjuvant immunotherapy trial design.
Extracellular Matrix News
Tumor Cell Apoptosis Modulates the Colorectal Cancer Immune Microenvironment via Interleukin-8-Dependent Neutrophil Recruitment
[Cell Death & Disease] The authors investigated the impact of apoptotic colorectal cancer cells on neutrophils and its consequence on other immune cells of the tumor microenvironment.