Tag results:
myeloid cells
Hematopoiesis News
High Glucose Macrophage Exosomes Enhance Atherosclerosis by Driving Cellular Proliferation & Hematopoiesis
[iScience] Infusions of bone marrow-derived macrophages exposed to high glucose increased hematopoiesis, circulating myeloid cell numbers, and atherosclerotic lesions with an accumulation of macrophage foam and apoptotic cells.
Muscle Cell News
Cell Type-Specific Roles of PAR1 in Coxsackievirus B3 Infection
[Scientific Reports] Investigators determined the effect of cell type-specific deletion of protease-activated receptor 1 (PAR1) in cardiac myocytes and cardiac fibroblasts on Coxsackievirus B3-induced myocarditis.
Neural Cell News
Characterization of Microglial Transcriptomes in the Brain and Spinal Cord of Mice in Early and Late Experimental Autoimmune Encephalomyelitis Using a RiboTag Strategy
[Scientific Reports] Scientists used a RiboTag strategy to characterize ribosome-bound mRNA only in microglia without incurring possible transcriptional changes after cell isolation.
Endothelial Cell News
The Zinc Finger Transcription Factor, KLF2, Protects against COVID-19 Associated Endothelial Dysfunction
[Signal Transduction and Targeted Therapy] Scientists demonstrated that the expression of KLF2 was reduced and monocyte adhesion was increased in endothelial cells treated with COVID-19 patient serum due to elevated levels of pro-adhesive molecules, ICAM1 and VCAM1.
Immunology of Infectious Disease News
Human Immunodeficiency Virus and Human Cytomegalovirus Coinfection of Infant Tonsil Epithelium May Synergistically Promote Both HIV-1 and HCMV Spread and Infection
[Journal of Virology] Scientists showed that cell-free HIV-1 and its proteins gp120 and tat induce the disruption of tonsil epithelial tight junctions and increase paracellular permeability, which facilitates HCMV spread within the tonsil mucosa.
Immune Regulation News
Polymeric Aggregate-Embodied Hybrid Nitric-Oxide-Scavenging and Sequential Drug-Releasing Hydrogel for Combinatorial Treatment of Rheumatoid Arthritis
[Advanced Materials] The rational design of an injectable in situ polymeric aggregate-embodied hybrid nitric oxide (NO)-scavenging and sequential drug-releasing gel platform for the combinatorial treatment of rheumatoid arthritis by incorporating a “clickable” NO-cleavable cross-linker was reported.