myeloid cells

[International Immunopharmacology] Scientists showed that TNF-α significantly reduced the expression of SIRT6 protein and mRNA in a concentration- and time-dependent manner and increased the expression of monocyte chemotactic protein 1, interleukin (IL) -6 and IL-1β in human umbilical vein endothelial cells.

[PLOS Biology] Scientists showed that LTB4 and its synthesizing enzymes localize to intracellular multivesicular bodies, which, upon stimulation, released their content as exosomes.

[Nature Biomedical Engineering] Scientists reported injectable biomaterial vaccines that triggered potent humoral and T-cell responses to bacterial antigens by recruiting, reprogramming and releasing dendritic cells.

[Cell] Investigators showed that GABA-receptive microglia selectively interacted with inhibitory cortical synapses during a critical window of mouse postnatal development.

[Journal of Enzyme inhibition and Medicinal Chemistry] A new generation of carbonic anhydrase inhibitors and acetazolamide were investigated in two models of brain ischaemia: in rat hippocampal acute slices exposed to severe oxygen, glucose deprivation and in an in vivo model of focal cerebral ischaemia induced by permanent occlusion of the middle cerebral artery in the rat.

[Platelets] Investigators found that the plant hormone abscisic acid could increase the generation of megakaryocytes and platelets from human iPSCs.