myeloid cells

[FEBS Journal] Investigators observed that the increase of Sox9 significantly promoted hepatocellular carcinoma cell growth and invasion in cell cultures, whereas knockdown of Sox9 showed the opposite effects, suggesting that Sox9 may regulate the proliferation and invasion of hepatoma cells in an autocrine manner.

[Experimental Cell Research] Flow cytometry and sphere formation assays indicated that LINC01232 significantly promoted non-small cell lung carcinoma cell stemness.

[Journal of Leukocyte Biology] Scientists present an overview of neutrophil heterogeneity and its impact on the course and severity of viral respiratory infectious diseases.

[Journal of Interferon and Cytokine Research] Investigators showed that CCL18 did not change the expression of the inflammatory factors, interleukin (IL)-1β, IL-6, tumor necrosis factor alpha, or inducible nitric oxide synthase, but significantly induced expression of the macrophage markers, MRC-1 and ARG-1 M2, in a human microglial clone 3 cell line

[Cell Reports] Scientists showed that the neuronal retromer could regulate Alzheimer's disease (AD)-associated pathologies in two of AD's principal cell types, which strengthened the link, and clarified the mechanism, between endosomal trafficking and late-onset sporadic AD.

[Science Advances] Investigators reported that exosomes from MSCs administered as eye drops notably alleviated graft-versus-host disease-associated dry eye disease by suppressing inflammation and improving epithelial recovery in mice and humans.