myeloid cells

[Bone Marrow Transplantation] Investigators analyzed 144 acute leukemia haploidentical hematopoietic-cell transplantation using post-transplant cyclophosphamide pediatric recipients; median age was ten years.

[Scientific Reports] The authors examined the benefits of serum-free conditioned medium from stem cells derived from human exfoliated deciduous teeth on a murine non-alcoholic steatohepatitis (NASH) model induced by a combination of Western diet and repeated administration of low doses of carbon tetrachloride intraperitoneally, focusing on the gut-liver axis.

[Cell Reports] Restoration of the gut bile acids pool attenuated severity of experimental autoimmune uveitis in association with inhibition of nuclear factor κB related pro-inflammatory cytokines in dendritic cells.

[Frontiers in Immunology] Analysis of fresh tumor samples from clear cell renal cell carcinoma patients unraveled the presence of a high frequency of tumor-infiltrating PD-L1+ natural killer (NK cells), suggesting that these NK cells might exhibit immunoregulatory functions.

[Nature Reviews Immunology] The authors highlight emerging functions of oxidized phosphocholines in dendritic cells and macrophages that drive unique inflammasome and migratory activities and hypermetabolic states.

[PLOS Pathogens] The authors reported that CXCR3-dependent recruitment of Ly6C+ Th1 effector cells was indispensable for concomitant immunity and acute cell-phagocyte interactions were critical to prevent the establishment of a permissive pathogen niche.