myeloid cells

[Cell Stem Cell] Xenotransplantation of human microglia into cerebral organoids allowed us to characterize key transcriptional programs of developing microglia in vitro and revealed that microglia induced transcriptional changes in neural stem cells and decrease interferon signaling response genes.

[Journal of Investigative Dermatology] Stimulator of IFN genes (STING) is a universal receptor that recognizes cytosolic DNA and triggers innate immune activation. Investigators elucidated the role of STING in the inflammation during psoriasis.

[Journal of Molecular and Cellular Cardiology] Investigators performed single-cell profiling of 35,245 cells from two venous malformation samples and three cavernous venous malformation samples, with a focus on endothelial cells, smooth muscle cells and immune microenvironment.

[Cell Reports] Scientists showed that critical COVID-19 was associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases.

[Nature Communications] Researchers developed a simple and robust human liver cell-based system modeling a clinical prognostic liver signature predicting long-term liver disease progression toward hepatocellular carcinoma.

[Cell Death Discovery] Scientists summarize the available data supporting the multiple effects of interleukin-34 in human colorectal carcinoma.