Tag results:
myocardium
ESC & iPSC News
CDH18 Is a Fetal Epicardial Biomarker Regulating Differentiation towards Vascular Smooth Muscle Cells
[NPJ Regenerative Medicine] Scientists recapitulated epicardiogenesis using human iiPSCs and identified type II classical cadherin CDH18 as a biomarker defining lineage specification in human active epicardium.
Mesenchymal Cell News
Irisin Promotes Cardiac Homing of Intravenously Delivered MSCs and Protects against Ischemic Heart Injury
[Advanced Science] The authors found that irisin pretreatment increased the cardiac homing of adipose tissue-derived MSCs administered by single and multiple intravenous injections to mice with myocardial ischemia-reperfusion (MI/R) by more than fivefold, which subsequently increased their antiapoptotic, proangiogenic, and antifibrotic effects in rats and mice that underwent MI/R.
Muscle Cell News
Molecular Mechanisms behind Persistent Presence of Parvovirus B19 in Human Dilated Myocardium
[Advances in Experimental Medicine and Biology] Researchers measured the levels of inflammation, fibrosis, apoptosis, and necrosis in endomyocardial biopsies and sera of nonischemic PVB19-positive and PVB19-negative dilated cardiomyopathy patients.
Muscle Cell News
A20 (TNFAIP3) Alleviates Viral Myocarditis through ADAR1/miR-1a-3p-Dependent Regulation
[BMC Cardiovascular Disorders] A20 was underexpressed and miR-1a-3p was overexpressed in the myocardium of VMC mice as well as in Coxsackie virus B3-infected cardiomyocytes.
Muscle Cell News
Aligned Human Induced Pluripotent Stem Cell-Derived Cardiac Tissue Improves Contractile Properties through Promoting Unidirectional and Synchronous Cardiomyocyte Contraction
[Biomaterials] Scientists fabricated aligned human cardiac tissue using a micro-processed fibrin gel with inverted V-shaped ridges and elucidated the effect of alignment control on contractile properties.
Mesenchymal Cell News
Sevoflurane Preconditioning Promotes Mesenchymal Stem Cells to Relieve Myocardial Ischemia/Reperfusion Injury via TRPC6-Induced Angiogenesis
[Stem Cell Research & Therapy] The authors investigated whether sevoflurane preconditioning could promote MSCs to attenuate myocardial I/R injury via transient receptor potential canonical channel 6 (TRPC6)-induced angiogenesis.