Scientists investigated the relationship between the expression levels of hsa_circ_0007456 in HCC and the susceptibility of NK cells, and found that the expression levels of hsa_circ_0007456 in HCC cell lines significantly influenced their susceptibility to NK cells.
[Cell Death & Disease]
Shi, M., Li, Z.-Y., Zhang, L.-M., Wu, X.-Y., Xiang, S.-H., Wang, Y.-G., & Zhang, Y.-Q. (2021). Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis. Cell Death & Disease, 12(1), 1–13. https://doi.org/10.1038/s41419-020-03334-8 Cite
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