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neural cells

Scaffolds Facilitate Epiretinal Transplantation of hiPSC-Derived Retinal Neurons in Nonhuman Primates

[Acta Biomaterialia] Researchers described the procedure and outcomes of human iPSC-derived retinal sheet transplantation in primate models using biodegradable materials.

Scientist Develops Human-Based Models to Study Neurodevelopmental Disorders

[Outlook India] Yogita K Adlakha, an Inspire Faculty Fellow, has developed human-based models to study neuron development and neurodevelopmental disorders such as autism, which can help design treatment strategies for such brain disorders, the Department of Science and Technology said.

Umbilical Cord Blood Therapy Modulates Neonatal Hypoxic Ischemic Brain Injury in Both Females and Males

[Scientific Reports] This study is the first preclinical evidence that umbilical cord blood could be an appropriate treatment for neonatal brain injury in both female and male neonates.

Maternal Immune Activation and Neuroinflammation in Human Neurodevelopmental Disorders

[Nature Reviews Neurology] The authors focus on the emerging human evidence for an association between maternal immune activation and childhood neurodevelopmental disorders, including autism spectrum disorder, attention-deficit/hyperactivity disorder and Tourette syndrome.

Fibro-Adipogenic Progenitors: Versatile Keepers of Skeletal Muscle Homeostasis, beyond the Response to Myotrauma

[Seminars in Cell & Developmental Biology] The authors review the emerging contribution of fibro-adipogenic progenitors to skeletal muscle responses to motor neuron injuries and to systemic physiological or pathological metabolic perturbations.

Casein Kinase 2 Dependent Phosphorylation of eIF4B Regulates BACE1 Expression in Alzheimer’s Disease

[Cell Death & Disease] Investigators provided clear evidence for the role of casein kinase 2 in the control of activity-driven BACE1 expression in cultured primary neurons, organotypic brain slices, and murine Alzheimer’s disease models.

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