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neurons

Regulation of Longevity by Depolarization-Induced Activation of PLC-β–IP3R Signaling in Neurons

[Proceedings of the National Academy of Sciences of the United States of America] The authors describe a mechanism by which depolarized neurons elevated the somatic ATP/ADP ratio in Drosophila glutamatergic neurons.

Hydrogen Sulfide Regulates Hippocampal Neuron Excitability via S-Sulfhydration of Kv2.1

[Scientific Reports] Functional experiments utilizing primary rat hippocampal neurons indicated that NaHS augmented action potential firing and thereby increased neuronal excitability.

Centrosome‐Mediated Microtubule Remodeling During Axon Formation in Human iPSC‐Derived Neurons

[EMBO Journal] The authors demonstrated that centrosomes played an essential role in controlling axon formation in hiPSC‐derived neurons.

Bisphenols Exert Detrimental Effects on Neuronal Signaling in Mature Vertebrate Brains

[Communications Biology] Investigators analyzed the effects of one month of exposition to BPA or BPS on an identified neuron in the vertebrate brain, using intracellular in vivo recordings in the uniquely suited Mauthner neuron in goldfish.

Attractor Cortical Neurodynamics, Schizophrenia, and Depression

[Translational Psychiatry] The author shows how understanding differences in the stability of attractor network systems in different brain areas can help to provide a scientific basis for relating some mental disorders to the operation of the underlying brain systems.

Early Stem Cell Aging in the Mature Brain

[Cell Stem Cell] Scientists pinpoint multiple factors that disrupted neural stem cell (NSC) behavior in the adult hippocampus. Clonal tracing showed that NSCs exhibited asynchronous depletion by identifying short-term NSCs and long-term NSCs.

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