Early Stem Cell Aging in the Mature Brain

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Scientists pinpoint multiple factors that disrupted neural stem cell (NSC) behavior in the adult hippocampus. Clonal tracing showed that NSCs exhibited asynchronous depletion by identifying short-term NSCs and long-term NSCs.
[Cell Stem Cell]
Ibrayeva, A., Bay, M., Pu, E., Jörg, D. J., Peng, L., Jun, H., Zhang, N., Aaron, D., Lin, C., Resler, G., Hidalgo, A., Jang, M.-H., Simons, B. D., & Bonaguidi, M. A. (2021). Early stem cell aging in the mature brain. Cell Stem Cell, 0(0). https://doi.org/10.1016/j.stem.2021.03.018 Cite
AbstractGraphical Abstract