NF-κB

[Cancer Cell International] Investigators discussed possible resistance mechanisms to trastuzumab and introduced mucin 1 (MUC1) as a potential target efficient for overcoming such resistance.

[inflammopharmacology] Researchers investigated the effect of curcumin on vascular smooth muscle cells inflammation induced by lipopolysaccharide and its mechanism.

[Molecular Cancer Research] Scientists reported a gatekeeper function of the Ras/Erk and NF-κB pathways pathways by working in synergy to suppress liver tumorigenesis.

[Scientific Reports] MiR-146a alleviated lung injury caused by respiratory syncytial virus (RSV) infection in young rats by targeting TRAF-6 and regulating JNK/ERK/MAPK signaling pathways.

[Science Signaling] Researchers demonstrated that PKCθ/β-dependent CARD11 phosphorylation also suppressed CARD11 functions in T or B cells.

[Stem Cell Reports] The authors findings supported a direct role for SARS-CoV-2 in mediating endothelial inflammation in an ACE2-dependent or -independent manner.