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organoids

Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver-Like Metabolic Biofactories

[Advanced Materials] Volumetric bioprinting via optical tomography shaped organoid-laden gelatin hydrogels into complex centimeter-scale 3D structures in under 20 seconds.

Electrophysiological Properties of Human Cortical Organoids: Current State of the Art and Future Directions

[Frontiers in Molecular Neuroscience] Investigators review existing data on the electrophysiological properties of neurons in human cortical organoids, as well as recent advances in the complexity of cortical organoid modeling that have led to improvements in functional maturation at single neuron and neuronal network levels.

Retinal Organoids Derived from Rhesus Macaque iPSCs Undergo Accelerated Differentiation Compared to Human Stem Cells

[Cell Proliferation] Retinal organoids produced from rhesus monkey iPSCs using established protocols differentiated through the stages of organoid development faster than those derived from human stem cells.

Force Generation Machinery Is Exploited by Cancer Cells Promoting Tumor Progression via ECM Remodeling and Immunosuppression

[Biophysical Journal] Researchers found that in addition to increased cell motility, cancer cells exploited the elevated actomyosin force generation to remodel ECM and to deplete important co-stimulatory receptors on antigen presenting cells, facilitating tumor progression.

The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome...

[mBio] Scientists reported a noninvasive technique to generate human nose organoids as an alternative to biopsy-derived organoids.

IL-22 Initiates an IL-18-Dependent Epithelial Response Circuit to Enforce Intestinal Host Defence

[Nature Communications] Scientists showed that IL-18 was a bona fide IL-22-regulated gate keeper for intestinal epithelial barrier.

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