p21

[Cell Death & Disease] Scientists clarified the role of KLHL38 in non-small cell lung cancer (NSCLC). KLHL38 expression was evaluated in tumor and adjacent normal tissues from 241 patients with NSCLC using immunohistochemistry and real-time PCR, and its association with clinicopathological parameters was analyzed.

[Nature Communications] Scientists demonstrated that local expression of the Yamanaka reprogramming factors, specifically in myofibers, induced the activation of muscle stem cells or satellite cells, which accelerated muscle regeneration in young mice.

[Scientific Reports] Investigators studied whether and to what extent the conditionally immortalized cell line hFOB 1.19 could serve as a surrogate model for bone-marrow derived MSCs.

[Food and Chemical Toxicology] Researchers indicated that a high level of glucose exposure does not effect the invasion and migration of PANC-1 cells, while aspartame increases both of these aggressiveness criterias.

[Aging] Investigators tested the anti-proliferative activity of capsanthin with human TNBC and found that cell proliferation was inhibited after 24, 48 and 72 h of treatment.

[Aging] A model of Ang II-induced vascular smooth muscle cell (VSMC) senescence and the renal artery of hypertensive patients were used to investigate the roles and mechanisms of circACTA2 and ILF3 in VSMC senescence. Investigators showed that circACTA2 expression was elevated in Ang II-stimulated VSMCs and in the vascular walls of hypertensive patients.