Tag results:
pancreatic cancer cells
Pancreatic Cell News
IMB5036 Inhibits Human Pancreatic Cancer Growth Primarily through Activating Necroptosis
[Basic & Clinical Pharmacology & Toxicology] MLKL inhibitor NSA attenuated the killing effect of IMB5036 on pancreatic cancer cells. IMB5036 stimulated translocation of MLKL and p-MLKL from cytoplasm to cell membrane.
Pancreatic Cell News
Glycosylation of MUC6 by α1,4-Linked N-acetylglucosamine Enhances Suppression of Pancreatic Cancer Malignancy
[Cancer Science] Investigators ectopically expressed α1,4-N-acetylglucosaminyltransferase (α4GnT), the α1,4-linked N-acetylglucosamine biosynthetic enzyme, together with MUC6 in the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, neither of which expressed α4GnT and MUC6.
Pancreatic Cell News
MCT4 as a Potential Therapeutic Target to Augment Gemcitabine Chemosensitivity in Resected Pancreatic Cancer
[Cellular Oncology] Investigators identified the prognostic significance and therapeutic options of metabolic subtypes of resectable pancreatic cancer.
Intestinal Cell News
HIG1 Domain Family Member 1A Disrupts Proliferation, Migration and Invasion of Colon Adenocarcinoma Cells
[Bioengineered] Higd-1a promotes the proliferation of pancreatic cancer cells and the growth of pancreatic cancer; however, no similar observations have been reported for colorectal cancer (CRC). This study, researchers verified the role of Higd-1a in colorectal cancer.
Pancreatic Cell News
MicroRNA-190b Expression Predicts a Good Prognosis and Attenuates the Malignant Progression of Pancreatic Cancer by Targeting MEF2C and TCF4
[Oncology Reports] Scientists examined the expression of miR‑190b in pancreatic cancer cell lines and tissues and evaluated its effects on cancer progression.
Pancreatic Cell News
ACY-241, an HDAC6 Inhibitor, Overcomes Erlotinib Resistance in Human Pancreatic Cancer Cells by Inducing Autophagy
[Archives of Pharmacal Research] Researchers evaluated the anticancer effect of ACY-241, an HDAC6-selective inhibitor, on erlotinib-resistant pancreatic cancer cells that overexpressed HDAC6.