IMB5036 Inhibits Human Pancreatic Cancer Growth Primarily through Activating Necroptosis

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MLKL inhibitor NSA attenuated the killing effect of IMB5036 on pancreatic cancer cells. IMB5036 stimulated translocation of MLKL and p-MLKL from cytoplasm to cell membrane.
[Basic & Clinical Pharmacology & Toxicology]
Abstract