Glycosylation of MUC6 by α1,4-Linked N-acetylglucosamine Enhances Suppression of Pancreatic Cancer Malignancy

Investigators ectopically expressed α1,4-N-acetylglucosaminyltransferase (α4GnT), the α1,4-linked N-acetylglucosamine biosynthetic enzyme, together with MUC6 in the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, neither of which expressed α4GnT and MUC6.