Tag results:
protein expression
Human Immunology News
NLRP3 Inflammasome Activation in Human Peripheral Blood Mononuclear Cells Induced by Venoms Secreted PLAM2s
[International Journal of Biological Macromolecules] Peripheral blood mononuclear cells were isolated by density gradient and incubated with RPMI, LPS, BthTX-I or BthTX-II isolated from Bothrops jararacussu venom, to evaluate viability, and the results showed that there was no cell death.
ESC & iPSC News
A Large Scale Mass Spectrometry-Based Histone Screening for Assessing Epigenetic Developmental Toxicity
[Scientific Reports] Scientists developed a mass spectrometry-based proof-of-concept to assess a histone code screening assay capable of simultaneously detecting multiple hPTM-changes in human ESCs.
Hepatic Cell News
Galectin-1 Confers Resistance to Doxorubicin in Hepatocellular Carcinoma Cells through Modulation of P-glycoprotein Expression
[Cell Death & Disease] Researchers investigated the molecular mechanism underlying galectin-1-mediated chemoresistance in hepatocellular carcinoma cells, particularly the involvement of P-glycoprotein in this effect.
Muscle Cell News
LncRNA ROR Modulates Myocardial Ischemia-Reperfusion Injury Mediated by the miR-185-5p/CDK6 Axis
[Laboratory Investigation] Researchers revealed that hypoxia/reoxygenation (H/R) treated human cardiac myocytes showed a significantly decreased miR-185-5p expression and increased expression of CDK6 and ROR.
Umbilical & Placental Cell News
Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation
[Stem Cell Reviews and Reports] The authors cross-compared transcriptomic and proteomic data and selected 26 candidate genes with the same expression trends in both omics analyses.
Prostate Cell News
Stage-Specific Differential Expression of Zinc Transporter SLC30A and SLC39A Family Proteins during Prostate Tumorigenesis
[Molecular Carcinogenesis] Investigators assessed the stage-specific expression of zinc transporters (ZNTs) belonging to the ZNT (SLC30A) and Zrt- and Irt-like protein (SLC39A) solute-carrier family in the prostate tissues of different genetically engineered mouse models of prostate cancer, their age-matched wild-type controls, and 104 prostate core biopsies from human patients with different pathological lesions.