Tag results:
protein expression
Muscle Cell News
PHLPP1 Deficiency Ameliorates Cardiomyocyte Death and Cardiac Dysfunction through Inhibiting Mcl-1 Degradation
[Cellular Signalling] Researchers found that PH domain leucine-rich repeat protein phosphatase1 (PHLPP1) deficiency enhanced Thr163 phosphorylation of Mcl-1, inhibited Mcl-1 degradation and maintained Mcl-1 protein expression level in myocardium and cardiomyocytes upon myocardial infarction or Dox treatment.
Intestinal Cell News
2′-Fucosyllactose Promotes Lactobacillus rhamnosus KLDS 8001 to Repair LPS-Induced Damage in Caco-2 Cells
[Journal of Food Biochemistry] Researchers investigated the effect of 2'-fucosyllactose on the repair of monolayer barrier damage in Caco-2 cells by Lactobacillus rhamnosus KLDS 8001 (KLDS 8001).
Mammary Cell News
NPY1R Exerts Inhibitory Action on Estradiol-Stimulated Growth and Predicts Endocrine Sensitivity and Better Survival in ER-Positive Breast Cancer
[Scientific Reports] Investigators demonstrated that Neuropeptide Y Receptor Y1 (NPY1R) mediated the inhibitory action of NPY on estradiol-stimulated growth of ER+ breast cancer (BC) cells, and its expression served as a biomarker to predict endocrine sensitivity and survival in ER+ BC patients.
Hepatic Cell News
Well-Differentiated Liver Cancers Reveal the Potential Link between ACE2 Dysfunction and Metabolic Breakdown
[Scientific Reports] Researchers analyzed angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 expression and localization in human liver cancers and in non-tumor livers.
Pancreatic Cell News
LncRNA MEG3 Regulates Autophagy and Pyroptosis via FOXO1 in Pancreatic β-Cells
[Cellular Signalling] Scientists investigated whether the lncRNA MEG3 could regulate autophagy and pyroptosis through FOXO1 in pancreatic β-cells.
Pulmonary Cell News
A Comparative Study on the Model of PM2.5 Direct or Indirect Interaction with Bronchial Epithelial Cells
[Environmental Science and Pollution Research] The authors examined the viability of BEAS-2B and mRNA/protein expression profile of oxidative stress and inflammatory response-related transcription factors Nrf2, NF-kB, and according inflammatory indicators such as IL-1, IL-6, and IL-8, with a view to evaluating the effects of different interaction models of PM2.5 on epithelial cell damage in vitro.