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qRT-PCR
Hematopoiesis News
Bone Mesenchymal Stem Cell-Derived Exosomal microRNA-7-5p Inhibits Progression of Acute Myeloid Leukemia by Targeting OSBPL11
[Journal of Nanobiotechnology] Researchers investigated the effects of exosomes derived from bone marrow mesenchymal stem cells on the regulation of acute myeloid leukemia and the underlying mechanisms mediated by microRNA.
Mammary Cell News
PBX3-Activated DLG1-AS1 Can Promote the Proliferation, Invasion and Migration of TNBC Cells by Sponging miR-16-5p
[Molecular Therapy Oncolytics] Scientists found that PBX3-activated DLG1-AS1 could promote the proliferation, invasion and migration of TNBC cells by sponging miR-16-5p and elevating JARID2 expression.
Mammary Cell News
Circular RNA circCCDC85A Inhibits Breast Cancer Progression via Acting as a miR-550a-5p Sponge to Enhance MOB1A Expression
[Breast Cancer Research] Researchers explored whether circCCDC85A could function as a miR-550a-5p sponge and influence breast cancer progression and found novel evidence that circCCDC85A inhibited the progression of breast cancer by functioning as a molecular sponge of miR-550a-5p to enhance MOB1A expression.
Pulmonary Cell News
Circ_0007385 Regulates Cell Proliferation, Apoptosis and Stemness via Targeting miR-493-3p/RAB22A Axis in Non-Small Cell Lung Cancer
[Thoracic Cancer] Expression levels of circ_0007385, microRNA-493-3p (miR-493-3p) and Ras-related protein Rab-22A (RAB22A) were detected by quantitative real-time polymerase chain reaction (qRT-PCR) in NSCLC tissues and cells.
Pulmonary Cell News
CircFBXW8 Acts an Oncogenic Role in the Malignant Progression of Non-Small Cell Lung Carcinoma by miR-370-3p-Dependent Regulation of TRIM44
[Biochemical Genetics] The authors investigated the role of circular RNA F-box and WD repeat domain containing 8 (circFBXW8) in NSCLC progression and the underlying mechanism.
Cancer Stem Cell News
MACC1 Regulates the AKT/STAT3 Signaling Pathway to Induce Migration, Invasion, Cancer Stemness, and Suppress Apoptosis in Cervical Cancer Cells
[Bioengineered] Researchers verified that treatment with the STAT3 activator had significant reversal effects on the malignant behaviors of cervical cancer (CC) cells and CC stemness.