The role of miR-30d in the proliferation and metastasis of pancreatic cancer cells was determined using in vitro and in vivo assays.
[Cell Death & Disease]
6807162 LNGS6ZCY items 1 apa default asc 1
Rosiglitazone significantly inhibited high glucose-induced proliferation, oxidative stress, inflammatory responses and extracellular matrix accumulation in mouse mesangial cells.
1254621 PZ5MN9CT items 1 apa default asc 1
Zhao, D., Guo, J., Liu, L., & Huang, Y. (2021). Rosiglitazone attenuates high glucose-induced proliferation, inflammation, oxidative stress and extracellular matrix accumulation in mouse mesangial cells through the Gm26917/miR-185-5p pathway. Endocrine Journal, advpub. https://doi.org/10.1507/endocrj.EJ20-0783 Cite
ox-LDL inhibited circRSF1 and histone deacetylase 1 (HDAC1) expression while upregulated miR-135b-5p expression in HUVECs.
6445212 9PU5W685 items 1 apa default asc 1
Zhang, X., Lu, J., Zhang, Q., Luo, Q., & Liu, B. (2021). CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis. Biological Research, 54(1), 11. https://doi.org/10.1186/s40659-021-00335-5 Cite
LINC01419 enhances the methylation of zinc finger of the cerebellum (ZIC1) promoter, inhibits ZIC1 expression, and activates the PI3K/Akt signaling pathway, thereby enhancing the malignant phenotypes of hepatocellular carcinoma cells in vitro as well as tumor formation and metastasis in vivo.
6606345 LXDMLVUX items 1 apa default asc 1
Through microarray analysis, investigators obtained the circRNA expression profile of lung adenocarcinoma and found that circ-HMGA2, a novel RNA, was highly expressed in lung adenocarcinoma.
[Cell Death & Disease]
6606345 XZPHIEUI items 1 apa default asc 1
Circ-HMGA2 (hsa_circ_0027446) promotes the metastasis and epithelial-mesenchymal transition of lung adenocarcinoma cells through the miR-1236-3p/ZEB1 axis | Cell Death & Disease. (n.d.). Retrieved March 25, 2021, from https://www.nature.com/articles/s41419-021-03601-2 Cite
Researchers demonstrated that tissue‑specific transplantation antigen P35B (TSTA3) was regulated by miR‑125a‑5p and functions as an oncogene in lung cancer via promoting the activation of β‑catenin signaling.
miR‑454‑3p overexpression led to the suppression of proliferation, migration, and invasion in A549 and NCI‑H1650 cells. The overexpression of miR‑454‑3p in A549 and NCI‑H1650 cells significantly inhibited EMT. TGFB2 was revealed to be a direct target of miR‑454‑3p by using TargetScan database and luciferase reporter assay.
Effects of intestinal epithelial cells transfected with metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) lentiviruses and Smart Silencer, on monolayer permeability and apical junction complex proteins were analyzed.
[Journal of Crohns & Colitis]
6445212 HESTGLKH items 1 apa default asc 1
Li, Y., Zhu, L., Chen, P., Wang, Y., Yang, G., Zhou, G., Li, L., Feng, R., Qiu, Y., Han, J., Chen, B., He, Y., Zeng, Z., Chen, M., & Zhang, S. (2021). MALAT1 maintains the intestinal mucosal homeostasis in Crohn’s disease via the miR-146b-5p-CLDN11/NUMB pathway. Journal of Crohn’s and Colitis, jjab040. https://doi.org/10.1093/ecco-jcc/jjab040 Cite
RNA_0074027 (Circ_0074027) interacted with microRNA-2467-3p (miR-2467-3p), and ras homolog family member A (RHOA) was a target of miR-2467-3p in NSCLC cells. RHOA silencing blocked the malignant potential of NSCLC cells. Circ_0074027 silencing restrained the malignant phenotypes of NSCLC cells largely through up-regulating miR-2467-3p.
[Journal of Bioenergetics and Biomembranes]
6606345 H9A2RWWF items 1 apa default asc 1
Circ_0074027 contributes to non‐small cell lung cancer progression through positively modulating RHOA via sequestering miR-2467-3p | SpringerLink. (n.d.). Retrieved March 11, 2021, from https://link.springer.com/article/10.1007%2Fs10863-021-09876-6 Cite
Curcumin inhibited NSCLC growth through downregulating circ-PRKCA, which regulated ITGB1 expression by adsorbing miR-384.
[Biomedicine & Pharmacotherapy]
6606345 AC974RQE items 1 apa default asc 1
Down-regulation of LINC01089 promoted the progression of NSCLC through regulating miR-152-3p/PTEN axis.
[Cancer Cell International]
6606345 J3JTAQ3K items 1 apa default asc 1