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SARS-CoV-2

Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection

[ACS Nano] The authors recently reported a SARS-CoV-2 human Fc-conjugated receptor-binding domain mRNA vaccine delivered via lipid nanoparticles.

SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation

[Cell Metabolism] Researchers describe the detection of SARS-CoV-2 viral antigen in pancreatic beta cells in autopsy samples from individuals with COVID-19.

SARS-CoV-2 Human T Cell Epitopes: Adaptive Immune Response against COVID-19

[Cell Host & Microbe] Investigators review how epitopes identified throughout the SARS-CoV-2 proteome reveal significant correlation between number of epitopes defined and size of the antigen provenance.

Immune Response to SARS-CoV-2 Variants of Concern in Vaccinated Individuals

[Nature Communications] The authors obtained serum and saliva samples from groups of vaccinated, infected and uninfected individuals and characterize the antibody response to receptor binding domain mutant strains.

Fab-Dimerized Glycan-Reactive Antibodies Are a Structural Category of Natural Antibodies

[Cell] Investigators describef HIV-1 Env Fab-dimerized glycan-reactive broadly neutralizing Ab without VH-swapped domains from simian-human immunodeficiency virus-infected macaques.

Humoral Immune Response to Circulating SARS-CoV-2 Variants Elicited by Inactivated and RBD-Subunit Vaccines

[Cell Research] The authors reportedthe humoral immune response to circulating SARS-CoV-2 variants, such as 501Y.V2, of the plasma and neutralizing antibodies elicited by CoronaV, ZF2001 and natural infection.

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