Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection

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The authors recently reported a SARS-CoV-2 human Fc-conjugated receptor-binding domain mRNA vaccine delivered via lipid nanoparticles.
[ACS Nano]
Elia, U., Rotem, S., Bar-Haim, E., Ramishetti, S., Naidu, G. S., Gur, D., Aftalion, M., Israeli, M., Bercovich-Kinori, A., Alcalay, R., Makdasi, E., Chitlaru, T., Rosenfeld, R., Israely, T., Melamed, S., Abutbul Ionita, I., Danino, D., Peer, D., & Cohen, O. (2021). Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection. Nano Letters. https://doi.org/10.1021/acs.nanolett.1c01284 Cite
AbstractGraphical Abstract