SARS-CoV-2

[Nature Reviews Immunology] The author covers recent developments in our understanding of the risks of SARS-CoV-2 infection in pregnancy, and how vaccination can reduce these.

[Nature Communications] The authors reported SARS-CoV-2 vaccine-induced immune responses and breakthrough infections in patients with inflammatory bowel disease, who were treated either with an anti-tumor necrosis factor antibody, infliximab, or with vedolizumab targeting a gut-specific anti-integrin that did not impair systemic immunity.

[Nature Immunology] Researchers showed that type 1 interferon regulated coinhibitory receptor expression on human T cells, inducing PD-1/TIM-3/LAG-3 while inhibiting T cell immunoreceptor with immunoglobulin and ITIM domains expression.

[Frontiers in Cellular and infection Microbiology] The authors established, from single biopsy specimens, a human adult stem cell-derived organoid model representing the upper respiratory airways and lungs and explored the applicability of this model to study respiratory virus infection.

[Cellular and Molecular Life Sciences] The author reviews some of the key pathways including the infectious and inflammatory processes that control hematopoiesis, followed by a comprehensive review that summarizes the latest evidence and discusses how SARS-CoV-2 infection impacts hematopoiesis.

[Biological Psychiatry] Although the vast majority of maternal immune activation model research is carried out in rodents, the nonhuman primate model has emerged in recent years as an important translational tool.