squamous cell carcinoma

[Journal of Cachexia Sarcopenia and Muscle] Genetically engineered and xenograft tumour models were used to explore the effect of interferon-induced protein with tetratricopeptide repeat 2-depleted metastatic oral squamous cell carcinoma on cancer cachexia.

[Scientific Reports] Cell cycle analyses revealed a marked G2/M arrest by plasma-activated medium and a clear apoptotic effect by the glycosylated indirubin derivative KD87 in human melanoma A375 and squamous cell carcinoma A431 cell lines.

[Genomics] To understand the role of cancer stem cells (CSCs) in the disease scientists have performed transcriptomics analysis on RNA-seq data from gingivobuccal oral squamous cell carcinoma primary tumors.

[NeoImmuneTech, Inc. (Businesswire, Inc.)] NeoImmuneTech, Inc. announced that the first patient has been dosed in the Phase IIa portion of a study evaluating NT-I7, a novel long-acting human interleukin-7, in combination with the PD-L1 targeting drug atezolizumab, in patients with advanced high-risk skin cancers including melanoma, merkel cell carcinoma, and cutaneous squamous cell carcinoma.

[Nature Communications] By utilizing a ΔNp63-specific conditional knockout mouse model and xenograft models of lung adenocarcinoma and squamous cell carcinoma, scientists found that ∆Np63 promoted NSCLC by maintaining the lung stem cells necessary for lung cancer cell initiation and progression in quiescence.

[Advances in Therapy] The authors analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.