stem cell markers

[Biomedicine & Pharmacotherapy] Homemade ethanol-based garlic extract was administered to MCF7 and MCF10DCIS breast tumor cell lines grown under moderate hypoxia. Cell cycle, epithelial-to-mesenchymal transition and cancer stem cell markers were evaluated.

[Cell Cycle] Investigators explored the role and underlying mechanism of miR-663a in the proliferation, migration, invasion, and cancer stem cell-like properties of glioma cells.

[Stem Cells and Development] Compared with tumor-adjacent normal tissues, death-associated protein kinase 1 (DAPK1) expression was reduced in prostate cancer cell lines with respect to that in normal prostate cells.

[Thrombosis Research] Scientists characterized the mechanisms behind prostate CSC-platelet interaction. Fluorescence Activated Cell Sorting was utilized to separate DU145 and PC3 prostate cancer cells into CD133+/CD44+, CD133+/CD44-, CD44+/CD133-, and CD133-/CD44- subpopulations and to measure their CXCR4 surface expression.

[Surgery] Expression of CSC markers was examined in 572 thyroid tumors from The Cancer Genome Atlas Thyroid Cancer database and tall cell variant and papillary thyroid carcinoma tumors by immunohistochemistry.

[Diabetologia] The authors investigated whether fenofibrate increased circulating hematopoietic stem/progenitor cells (HSPCs). When compared with placebo, fenofibrate significantly increased levels of HSPCs expressing CD34 and/or CD133.