stroke

[Pediatric Research] Different immune cell subsets in perinatal brain injury including their infiltration routes are reviewed and critical aspects such as sex differences and maturational stage are discussed.

[European Journal of Neurology] The authors screened the circular RNAs (circRNA) influencing matrix metalloproteinase-9 (MMP9) through the competing endogenous RNA network and evaluated the prognostic value of these circRNAs for acute ischemic stroke.

[Journal of the American Heart Association] The percentage of Tregs in the spleen, blood, and brain was detected using flow cytometry, and the number of Tregs in the ischemic hemisphere was counted using transgenic mice with an enhanced green fluorescent protein‐tagged Foxp3.

[Molecular Neurobiology] Due to paucity of standard protocols in extraction procedures of extracellular vesicles (EVs) and their pharmacological properties and mechanisms, the development of new EV dependent therapies is challenging.

[Molecular Psychiatry] The authors describe the current knowledge of the effects of aging on the immune system and the cerebral vasculature and how these changes alter the immune response to stroke and vascular dementia in animal and human studies.

[Experimental Neurology] The authors elucidated the impact of neurotrophin-3 on human monocyte and T cell activation as well as cytokine production ex vivo after stroke.