Tag results:

stroke

Strategies to Improve the Efficiency of Transplantation with Mesenchymal Stem Cells for the Treatment of Ischemic Stroke: A Review of Recent Progress

[Stem Cells International] The authors provide an overview of recent scientific reports concerning novel strategies that promote MSC transplantation as an effective therapeutic approach, including physical approaches, chemical agents, traditional Chinese medicines and extracts, and genetic modification.

NIH Research Projects on Interoception to Improve Understanding of Brain-Body Function

[National Institutes of Health] The National Institutes of Health is awarding seven projects a total of $18.15 million over five years to a new effort focused on interoception — the ways in which organisms sense and regulate signals within their bodies. One project will investigate the functional identification of vagal sensory neurons innervating the liver.

KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression

[Thrombosis and Haemostasis] Utilizing stasis-induced murine deep vein thrombosis model and cultured endothelial cells, scientists identified an increase of KLF11 expression under prothrombotic conditions both in vivo and in vitro.

Increased Expression of Fragmented tRNA Promoted Neuronal Necrosis

[Cell Death & Disease] Through a genome-wide small RNA sequencing, researchers identified several tRNA-derived fragments and piwi-interacting RNA species were enriched in glutamate-induced neuronal necrosis in rat primary neuron cultures, and this enrichment was dependent on the H3K4me3 increase.

Benign and Malignant Hematologic Manifestations in Patients with VEXAS Syndrome Due to Somatic Mutations in UBA1

[Blood Advances] Patients with VEXAS syndrome had a propensity toward developing cytopenia, myelodysplastic syndrome, multiple myeloma, and venous thromboembolism. Bone marrow from patients with VEXAS showed characteristic vacuolization of myeloid and erythroid precursors.

Zeb2/Axin2-Enriched BMSC-Derived Exosomes Promote Post-Stroke Functional Recovery by Enhancing Neurogenesis and Neural Plasticity

[Journal of Molecular Neuroscience] After stimulation with Zeb2/Axin2-enriched BMSC exosomes, the spatial memory and nerve function of MCAO rats showed marked recovery. The number of neurons was increased in the subventricular zone, hippocampus, and cortex area, while the expression of nerve growth factors was upregulated.

Popular