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TNF-α

Catalpol Protects AC16 Cells from Hypoxia/Reoxygenation Injury by Regulating the miR-22-3p/DPP4 Axis

[Journal of Biochemical and Molecular Toxicology] Catalpol promoted the viability and reduced cell apoptosis of human cardiomyocyte AC16 cells and repressed the release of inflammatory cytokines TNF-α, IL-6, and IL-1β, while inhibiting the leakage of myocardial injury markers lactate dehydrogenase and creatine kinase.

LncRNA Rian Reduces Cardiomyocyte Pyroptosis and Alleviates Myocardial Ischemia–Reperfusion Injury by Regulating by the miR-17-5p/CCND1 Axis

[Hypertension Research] The authors investigated the mechanism of long noncoding RNAs Rian in myocardial ischemia–reperfusion injury-induced cardiomyocyte pyroptosis.

HDAC11 Promotes Both NLRP3/Caspase-1/GSDMD and Caspase-3/GSDME Pathways Causing Pyroptosis via ERG in Vascular Endothelial Cells

[Cell Death Discovery] Researchers investigated the role of histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.

LncRNA NEAT1-Associated Aerobic Glycolysis Blunts Tumor Immunosurveillance by T Cells in Prostate Cancer

[Neoplasia] Nuclear enriched abundant transcript 1 (NEAT1) depletion inhibited prostate cancer cell aerobic glycolysis accompanied by the reduction of lactate levels in the medium.

Characterization of the MicroRNA Profile of Ginger Exosome-Like Nanoparticles and Their Anti-inflammatory Effects in Intestinal Caco-2 Cells

[Journal of Agricultural and Food Chemistry] The miRNA profiles in ginger and ginger exosome-like nanoparticles were analyzed using high-throughput sequencing, and the results of the sequencing were validated by real-time quantitative polymerase chain reaction.

Knockdown of Circ_0001679 Alleviates Lipopolysaccharide-Induced MLE-12 Lung Cell Injury by Regulating the miR-338-3p/ Mitogen-Activated Protein Kinase 1 Axis

[Bioengineered] Researchers indicated that circ_0001679/miR-338-3p/MAPK1 axis may play an important role in the pathogenesis of acute lung injury.

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