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TNF-α
Muscle Cell News
Catalpol Protects AC16 Cells from Hypoxia/Reoxygenation Injury by Regulating the miR-22-3p/DPP4 Axis
[Journal of Biochemical and Molecular Toxicology] Catalpol promoted the viability and reduced cell apoptosis of human cardiomyocyte AC16 cells and repressed the release of inflammatory cytokines TNF-α, IL-6, and IL-1β, while inhibiting the leakage of myocardial injury markers lactate dehydrogenase and creatine kinase.
Muscle Cell News
LncRNA Rian Reduces Cardiomyocyte Pyroptosis and Alleviates Myocardial Ischemia–Reperfusion Injury by Regulating by the miR-17-5p/CCND1 Axis
[Hypertension Research] The authors investigated the mechanism of long noncoding RNAs Rian in myocardial ischemia–reperfusion injury-induced cardiomyocyte pyroptosis.
Endothelial Cell News
HDAC11 Promotes Both NLRP3/Caspase-1/GSDMD and Caspase-3/GSDME Pathways Causing Pyroptosis via ERG in Vascular Endothelial Cells
[Cell Death Discovery] Researchers investigated the role of histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.
Prostate Cell News
LncRNA NEAT1-Associated Aerobic Glycolysis Blunts Tumor Immunosurveillance by T Cells in Prostate Cancer
[Neoplasia] Nuclear enriched abundant transcript 1 (NEAT1) depletion inhibited prostate cancer cell aerobic glycolysis accompanied by the reduction of lactate levels in the medium.
Intestinal Cell News
Characterization of the MicroRNA Profile of Ginger Exosome-Like Nanoparticles and Their Anti-inflammatory Effects in Intestinal Caco-2 Cells
[Journal of Agricultural and Food Chemistry] The miRNA profiles in ginger and ginger exosome-like nanoparticles were analyzed using high-throughput sequencing, and the results of the sequencing were validated by real-time quantitative polymerase chain reaction.
Pulmonary Cell News
Knockdown of Circ_0001679 Alleviates Lipopolysaccharide-Induced MLE-12 Lung Cell Injury by Regulating the miR-338-3p/ Mitogen-Activated Protein Kinase 1 Axis
[Bioengineered] Researchers indicated that circ_0001679/miR-338-3p/MAPK1 axis may play an important role in the pathogenesis of acute lung injury.