TNF-α

[Regenerative Medicine] A murine model of a skin wound was treated with a combination of extract of astragalus and exosomes of MSCs. CD11b+ and CD45 macrophages were detected and levels of cytokines were tested.

[Skin Pharmacology and Physiology] Scientists investigated the role and regulatory relationship between long noncoding RNA (lncRNA) XIST and miR-338-5p in psoriatic patients and cell models.

[Stem Cell Research & Therapy] The authors performed a Phase I/IIa non-randomized, open-label study to evaluate the safety and efficacy of a single, intravenous infusion of autologous, adipose-derived MSCs over a period of 52 weeks, in patients with active rheumatoid arthritis.

[Scientific Reports] MiR-146a alleviated lung injury caused by respiratory syncytial virus (RSV) infection in young rats by targeting TRAF-6 and regulating JNK/ERK/MAPK signaling pathways.

[Journal of Reproductive Immunology] Investigators hypothesized that decidual leukocytes were altered by maternal SARS-CoV-2 infection in pregnancy and that this decidual immune response was shaped by the timing of infection during gestation.

[Circulation Research] Mouse models of atherosclerosis in endothelial cell-specific-Bach1 knockout mice were used to study the role of BTB and CNC homology 1 (BACH1) in the regulation of atherogenesis and the underlying mechanisms.