Publication

[In Vitro Cellular & Developmental Biology - Animal] Researchers applied CDKi within a specific time window, which improved the efficiency of pancreatic endocrine cell induction. CDKi treatment reduced the prevalence of multi-layered regions and enhanced expression of PDX1 and NGN3.

[Scientific Reports] Researchers examined the effect of IL-1β stimulated hUCMSCs (IL-1β-hUCMSCs) on immunoregulation of M1 and M2 macrophages in vitro and in the rheumatoid arthritis mouse model.

[International Journal Of Oncology] Human colorectal cancer cell lines HCT116 and HT29 were transfected with RPL27‑specific small interfering RNA and proliferation was assessed in vitro and in vivo using proliferation assays, fluorescence‑activated cell sorting and a xenograft mouse model.

[Chinese Medical Journal] The stiffness of bladder cancer cells was determined by atomic force microscopy (AFM). The modified microfluidic chip was utilized to separate soft cells, and the 3D Matrigel culture system was to maintain the softness of tumor cells.

[Dalton Transactions] Scientists reported the synthesis, characterisation, and anti-breast CSC properties of a series of copper(II)-terpyridine complexes containing aryl sulfonamide groups. All of the copper(II)-terpyridine complexes adopt distorted square pyramidal geometries and are suitably stable in biologically relevant solutions.

[International Journal Of Stem Cells] Using the Cancer Genome Atlas database, investigators found higher expression of PTHrP in GBM, which correlated inversely with survival. Glioblastoma stem cells were established from three human glioblastoma samples obtained after surgical resection.