Publication

[International Immunopharmacology] Researchers focused on the outer membrane proteins Omp25 and BP26 of Brucella as targets, employing a multidimensional strategy to develop novel mRNA vaccines and systematically evaluate their immunoprotective efficacy.

[Vaccine] Scientists reported that multi-subtype neuraminidase and M2 ectodomain repeatvirus-like particle vaccine conferred higher efficacy of broad cross-protection after two doses of intranasal delivery than intramuscular injection.

[Medical Microbiology and Immunology] Investigators studied the impact of Staphylococcus aureus colonization and abscess events on plasma anti-αGal antibody levels.

[Nature Communications] Scientists showed that during somatic embryogenesis induced by overexpressing the totipotency-regulating transcription factor LEAFY COTYLEDON2 (LEC2) in Arabidopsis, CHH hypermethylation is deposited by the LEC2-activated RNA-directed DNA methylation pathway.

[Biological Research] Researchers disturbed the nicotinamide phosphoribosyltransferase (NAMPT) activity and employed immunofluorescence staining and live cell imaging to explore its roles during early embryo development.

[Circulation] Cardiomyocyte-specific N6-adenosine-methyltransferase-like 3 (METTL3) knockout mice and their wild-type littermates were subjected to either chow diet or high-fat diet feeding and injection of streptozotocin to induce diabetic cardiomyopathy.