Publication

[BMC Cancer] Researchers provided insights into the transcriptomic features of TMEM173 in the bone marrow of high-risk B-cell acute lymphoblastic leukemia (B-ALL) patients. Targeted activation of TMEM173 in specific cells might provided new therapeutic strategies for B-ALL patients.

[Nature Medicine] This Phase III study was designed to compare the safety and efficacy of motixafortide + granulocyte colony-stimulating factor (G-CSF) versus placebo + G-CSF in patients with multiple myeloma undergoing hematopoietic stem progenitor cell mobilization before autologous hematopoietic stem cell transplantation.

[Transplantation And Cellular Therapy] Scientists reported the results of a retrospective analysis on second allogeneic transplantation treated with total marrow irradiation as a myeloablative conditioning regimen, intending to limit toxicity.

[Advanced Science] Scientists developed polydimethylsiloxane substrates with different stiffnesses, and investigated the tenogenic differentiation of MSCs exposed to different stiffnesses and macrophage paracrine signals.

[Stem Cell Research & Therapy] Scientists cultured MSCs with/without uncommitted M0 macrophages, and with/without contaminated polyethylene particles in a 3D gelatin methacrylate constructs/scaffolds.

[Stem Cell Research & Therapy] The authors used human adipose-derived MSCs to address the role of G4 motifs during adipogenic differentiation.