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Translocation across a Human Enteroid Monolayer by Zoonotic Streptococcus suis Correlates with the Presence of Gb3-Positive Cells

[iScience] In a human enteroid model, scientists reported that the zoonotic clonal complex 1 (CC1) genotype had a 40% higher translocation frequency than the non-zoonotic CC16 genotype.

Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells

[Molecular And Cellular Biology] Researchers investigated the regulation of forkhead box A1 (FOXA1) expression in colorectal cancer (CRC), focusing on well-differentiated CRC cells, where FOXA1 was robustly expressed.

Cold Atmospheric Plasma Stabilizes Mismatch Repair for Effective, Uniform Treatment of Diverse Colorectal Cancer Cell Types

[Scientific Reports] The authors reported that cold atmospheric plasma treatment induced comparable effects on apoptosis, reactive oxygen species and reactive nitrogen species, as well as the expression of apoptosis-related proteins in both microsatellite instability and microsatellite stability cells.

OLFM2 Promotes Epithelial-Mesenchymal Transition, Migration, and Invasion in Colorectal Cancer through the TGF-β/Smad Signaling Pathway

[BMC Cancer] Knockdown and overexpression olfactomedin 2 (OLFM2) cell lines were constructed using small interfering RNA and overexpression plasmids to explore the role of OLFM2 in the migration and invasion of colorectal cancer through transwell, and wound healing experiments.

Identification of Direct Connections between the Dura and the Brain

[Nature] Using transcriptomic data, the authors developed transgenic mice to examine specific anatomical structures that function as routes across the arachnoid barrier.

Utilizing Human-Induced Pluripotent Stem Cells to Study Cardiac Electroporation Pulsed-Field Ablation

[Circulation-Arrhythmia And Electrophysiology] Human-induced pluripotent stem cells-derived cardiomyocytes were seeded as circular cell sheets and subjected to different pulsed-field ablation protocols.

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