Publication

[Journal For Immunotherapy Of Cancer] Investigators highlighted the interaction between bipositive TAMs or cancer cells and T cells was predominantly focused on FXYD6+ T cells rather than regulatory T cells, whereas, FXYD6+ T cells were further identified as a group of novel immunosuppressive T cells.

[Advanced Materials] Investigators developed pathogenic tau-specific autophagy based on customized nanochaperone for Alzheimer’s disease treatment.

[Science Advances] Scientists designed a seven-residue D-TLKIVWC peptide, which not only prevented tau aggregation but also fragmented tau fibrils extracted from Alzheimer’s disease brains to neutralize their seeding ability and protect neuronal cells from tau-induced toxicity.

[Cell Reports] Investigators showed that the Mediator Med23 was critically important for muscle stem cell (MuSC)-mediated muscle regeneration. Med23 was increasingly expressed in activated/proliferating MuSCs on isolated myofibers or in response to muscle injury.

[Circulation] The authors used smooth muscle cell (SMC) lineage tracing mice and human tissues and applied a range of methods, including molecular, cellular, histological, computational, human genetics, and pharmacological approaches, to investigate the features of SMC-derived cells in atherosclerosis.

[Advanced Science] A system was described for differentiating hiPSCs on new generation laminin fragments, a recombinant form of a laminin E8 fragment conjugated to the heparan sulfate chains attachment domain of perlecan.