Publication

[Stem Cells Translational Medicine] The authors discovered that silicate microfiber scaffolds could support the formation of cortical neuronal layers and successfully generated cortical neuronal layers, which were nine times thicker than conventional cerebral organoids, in 70 days.

[EMBO Journal] Scientists showed that exposure to a solubilized basement membrane matrix substrate, Matrigel, at early neuroepithelial stages caused rapid tissue polarization and rearrangement of neuroepithelial architecture.

[Nature Medicine] MAESTRO-NAFLD-1 was a 52-week randomized, double-blind, placebo-controlled phase III trial evaluating the safety of resmetirom in adults with nonalcoholic fatty liver disease (NAFLD) and presumed nonalcoholic steatohepatitis.

[Acta Pharmacologica Sinica] Scientists investigated the mechanisms of occurrence and development of acute liver injury (ALI) in lipopolysaccharide-induced ALI mice.

[Advanced Healthcare Materials] In vitro, zinc extraction promoted the proliferation and migration of HUVECs and upregulated the key gene for tube formation HIF-1α and VEGF-A, with a peak concentration of 22.5 μм.

[Biomedicine & Pharmacotherapy] Researchers investigated the potential protective effects of 5-Bromo-3,4-dihydroxybenzaldehyde on diabetic retinopathy using primary human retinal vascular endothelial cells and retinal tissue explants.