Publication

[NPJ Precision Oncology] Investigators leveraged machine-learning tools by evaluating expression of genes of pharmacological relevance to standard-AML chemotherapy in a discovery-cohort of pediatric AML patients and defined a 5-gene-drug resistance score that was predictive of outcome.

[Cancer Research] Scientists showed that targeting glutamine utilization stimulated Yes-associated protein (YAP) signaling in cancer cells by reducing cyclic adenosine monophosphate/protein kinase A-dependent phosphorylation of large tumor suppressor.

[Scientific Reports] Investigators identified the most consistently expressed genes by utilizing multiple published RNA-seq data of chicken liver and Leghorn Male Hepatoma cells.

[Science Translational Medicine] By integrating data from myofiber force measurements, x-ray diffraction experiments, and biochemical assays with clinical data, researchers found that in myofibers isolated from the diaphragm of ventilated ICU patients, myosin was trapped in an energy-sparing, super-relaxed state, which impaired the binding of myosin to actin during diaphragm contraction.

[Lab On A Chip] The authors presented a straightforward and cost-effective elastomer replica molding method utilizing commercially available optical discs to generate various nanopatterns, such as nanogroove/ridge, nanoposts, and nanopits, varying in spacing and heights.

[Redox Biology] Simultaneous label-free autofluorescence multiharmonic microscopy was used to provide rich intracellular information based on endogenous contrasts.