Review

[Nature Cardiovascular Research] Scientists highlight approaches to examine ECM mechanics at tissue and cellular levels, focusing on how mechanical interactions between cells and the ECM regulate vascular phenotype, especially under certain pathological conditions.

[Experimental Hematology & Oncology] Scientists focus on recent advances in the application of organoids in cancer research and discuss the opportunities and challenges facing organoid research.

[Cell Proliferation] The authors describe the possible roles of enteric glial cells in the pathogenesis of Crohn's disease, including the roles of glia–immune interactions, neuronal modulation, neural plasticity, and barrier integrity.

[Cellular Signalling] The authors highlight the common pathways between cachexia and breast cancer stem cell signaling, to identify potential therapeutic targets that can aid both conditions.

[Stem Cell Reports] The authors outline the regulations related to PSC-derived cell-based therapeutic products in the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use founding regions, US, EU/UK, and Japan,

[Bioengineering & Translational Medicine] The authors summarize the current understanding of potential mechanisms that drive SARS-CoV-2-induced cardiac dysfunction based on in vitro studies.