Review

[Blood] The authors review the emerging applications of single cell techniques, and early results related to disease pathogenesis: effector and target cell populations and relationships; cell-autonomous and non-autonomous phenotypes in clonal hematopoiesis; transcript splicing; chromosomal abnormalities; TCR usage, and clonality.

[Journal of Translational Medicine] Scientists summarize aging-related changes in the composition, structure, and function of the extracellular matrix and their relevance for angiogenesis.

[BMEMat] Investigators summarize recent advances in biomaterials for in situ cell therapy including T cells, macrophages, dendritic cells, and stem cells reprogramming leveraging lipid nanoparticles, polymers, inorganic materials, and other biomaterials.

[Medicinal Research Reviews] The authors summarize the roles of β-blockers in soft tissue wound healing and explore their clinical applications.

[Fundamental & Clinical Pharmacology] The authors elucidate the mechanisms involved in skeletal muscle wasting phenomenon over the last few years and review different pathways responsible for muscle atrophy in cancer cachexia.

[Oncogene] Scientists highlight the current in vitro 3D prostate cancer (PCa) models with a special focus on organoids and discuss engineering approaches to create more physiologically relevant PCa organoid models.