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Common Signaling Pathways Involved in Alzheimer’s Disease and Stroke: Two Faces of the Same Coin

[Journal Of Alzheimers Disease] The authors summarized the most common signaling cascades including autotoxicity, ApoE4, insulin signaling, inflammation, mTOR-autophagy, notch signaling, and microbiota-gut-brain axis, present in both Alzheimer's disease and ischemic stroke.

Genetically Engineered Neural Stem Cells (NSCs) Therapy for Neurological Diseases; State-of-the-Art

[Biotechnology Progress] Investigators review the therapeutic capability of genetically modified neural stem cells (NSCs) rather than naïve NSCs in neurological disease beyond brain tumors and shed light on the recent progress and prospect in this context.

Regulatory T Cells in Parasite Infections: Susceptibility, Specificity and Specialisation

[Trends in Parasitology] Scientists discuss how the susceptibility to many parasite infections is controlled by regulatory T cells, and the role they play in moderating the immunopathological consequences of parasitism, and dampening bystander reactions in an antigen-nonspecific manner.

T Cell-Mediated Immunity during Epstein–Barr Virus Infections in Children

[Infection Genetics And Evolution] Investigators summarize T cell immunity in common Epstein–Barr virus (EBV)-associated diseases in children, including IM, chronic active EBV infection and EBV-associated hemophagocytic lymphohistiocytosis.

Epigenetic Regulation in the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Targets

[Signal Transduction and Targeted Therapy] Investigators present an up-to-date and thorough description of how epigenetic modifications in tumor cells influence immune cell responses in the tumor microenvironment.

Telomerase-Targeted Therapies in Myeloid Malignancies

[Blood Advances] The authors summarize telomere and telomerase biology as it relates to both physiologic and malignant cells. They discuss the development of telomere and telomerase targeted therapeutic candidates within the realm of myeloid malignancies.

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