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Review

Extracellular Vesicles As Tools and Targets in Therapy for Diseases

[Signal Transduction And Targeted Therapy] The authors discuss in detail the roles of extracellular vesicles across various conditions, including cancers, neurodegenerative disorders, diabetes, viral infections, and autoimmune and renal diseases, emphasizing the potential advancements in molecular diagnostics and drug delivery.

Induced-Pluripotent Stem Cells and Neuroproteomics as Tools for Studying Neurodegeneration

[Academic Radiology] Investigators highlight studies from the past sive years on the contributions of iPSCs within neuroproteomic investigations, which uncover the molecular mechanisms behind neurodegenerative llnesses.

Inhibitor of PD-1/PD-L1: A New Approach May Be Beneficial for the Treatment of Idiopathic Pulmonary Fibrosis

[Journal Of Translational Medicine] The authors discuss the application of PD-1/PD-L1 checkpoint in idiopathic pulmonary fibrosis, with the aim of finding a new direction for idiopathic pulmonary fibrosis treatment.

The Yin and Yang of Chromosomal Instability in Prostate Cancer

[Nature Reviews Urology] In the context of prostate cancer, studies indicate that chromosomal instability has a key role in disease progression and might also offer a therapeutic vulnerability that can be pharmacologically targeted.

Decoding Leukemia at the Single-Cell Level: Clonal Architecture, Classification, Microenvironment, and Drug Resistance

[Experimental Hematology & Oncology] The authors provide a comprehensive summary of current single-cell studies on leukemia and highlight the markers and mechanisms that show promising clinical implications for the diagnosis and treatment of leukemia.

Progress in Cardiac Tissue Engineering and Regeneration: Implications of Gelatin-Based Hybrid Scaffolds

[International Journal Of Biological Macromolecules] Scientists review state-of-the-art gelatin/GelMA-based hybrid scaffolds currently applied for cardiac tissue engineering and regenerative therapy.

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