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Shaping the Neurovascular Unit Exploiting Human Brain Organoids

[Molecular Neurobiology] Scientists highlight the importance of studying the neurovascular unit in a forward-looking perspective of leveraging their use for understanding and treating neurological disorders.

Regulation of Autoimmune-Mediated Neuroinflammation by Endothelial Cells

[European Journal of Immunology] The authors discuss how endothelial cells regulate the migration and the functions of T cells in the CNS both at steady-state and in murine models of neuroinflammation, with a special focus on the anatomical, cellular, and molecular mechanisms implicated in EAE.

Epithelial Metabolism as a Rheostat for Intestinal Inflammation and Malignancy

[Trends In Cell Biology] The authors review the execution of intestinal epithelial metabolism in health and illustrate how perturbation of epithelial metabolism affects experimental gut inflammation and tumorigenesis.

Effects of Apigenin on Gastric Cancer Cells

[Biomedicine & Pharmacotherapy] Scientists systematize the available data regarding the effects of apigenin on gastric cancer cells, in terms of cell proliferation, apoptosis, Helicobacter pylori infection, and molecular targets.

The Structure and Function of Lamin A/C: Special Focus on Cardiomyopathy and Therapeutic Interventions

[Life Sciences] Scientists focus on the structural organization, expression pattern, and function of lamin A/C, its interacting partners, and the pathophysiology associated with mutations in the lamin A/C gene, with special emphasis on cardiovascular diseases.

Nuclear Mechanotransduction on Skin Stem Cell Fate Regulation

[Current Opinion In Cell Biology] Scientists focus on the key cytoplasmic and nuclear mechanosensitive structures that are critical for the mammalian skin development and homeostatic maintenance.

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