Publication

[Nature] Using transcriptomic data, the authors developed transgenic mice to examine specific anatomical structures that function as routes across the arachnoid barrier.

[Circulation-Arrhythmia And Electrophysiology] Human-induced pluripotent stem cells-derived cardiomyocytes were seeded as circular cell sheets and subjected to different pulsed-field ablation protocols.

[Nature] Scientists investigated 136 variables and identified smoking, cytomegalovirus latent infection and body mass index as major contributors to variability in cytokine response, with effects of comparable magnitudes with age, sex and genetics.

[Cell Death & Disease] Researchers demonstrated that methyltransferase-like 3 was highly expressed in CD44(+) cells and promoted CSCs phenotype. Using RNA-sequencing analysis, they showed that Spalt-like transcription factor 4 (SALL4) was involved in the maintenance of CSCs properties.

[Nature Chemical Biology] Researchers reported that O-GlcNAc modification of α-synuclein monomers resulted in the formation of amyloid fibril with distinct core structure, as revealed by cryogenic electron microscopy, and diminished seeding activity in seeding-based neuronal and rodent models of Parkinson’s disease.

[Cell Death & Disease] Investigators found that MPN domain-containing protein 1 (Mysm1) was expressed in neural stem cells and its expression was increased with age in mice.