Publication

[Journal Of Orthopaedic Research] MSC-laden DWIVA peptide-functionalized hydrogels presented rapidly induce targeted bone formation and have the potential to form nascent bone within bones in jeopardy of an osteoporotic fracture such as the femur.

[Scientific Reports] Researchers showed that microtubule associated monooxygenase, calponin and LIM domain containing 2 (MICAL2) was highly expressed in pancreatic cancer tissue and exhibited potential diagnostic capability. High expression of MICAL2 was also associated with poor prognosis and acted as an independent prognostic factor.

[Blood Advances] The authors generated iPSCs from healthy fetal liver (FL) cells and produced isogenic primitive or definitive red blood cells (RBCs) which were compared directly to the FL-derived RBCs.

[Experimental Cell Research] Researchers examined the electrophysiological mechanism of Early repolarization syndrome (ERS) utilizing iPSCs and CRISPR/Cas9 genome editing. Whole genome sequencing was used to identify the DPP6 variant in four families with sudden cardiac arrest induced by ERS.

[Current Stem Cell Research & Therapy] With NKX2.5eGFP H9 hESCs, investigators established single and double knockout cell lines for HAND1 and HAND2, respectively, whose cardiomyocyte differentiation efficiency could be monitored by assessing NKX2.5-eGFP+ cells with flow cytometry.

[Nature Communications] Investigators demonstrated that teratomas derived from aneuploid murine ESCs, but not from isogenic diploid ESCs, disseminated to multiple organs, for which no additional copy number variations were required.