Publication

[Journal of Steroid Biochemistry and Molecular Biology] Scientists elucidated the effects of acupuncture on the protein and gene expression of estrogen receptors alpha and beta in testosterone-induced benign prostatic hyperplasia in rat models.

[Journal Of Materials Science-Materials In Medicine] Experiments in vitro showed that DTX-loaded poly-Tetraethylene glycol nanoparticles had good compatibility to healthy cells and strong anti-tumor effect.

[Biochemical and Biophysical Research Communications] Investigators elucidated the effects of senescence induction on proliferation, cell cycle, and apoptosis in prostate cancer stem cells (CSCs) and non-CSCs.

[Immunological Investigations] Using CRPC cell lines, the transwell chamber experiments revealed ataxia telangiectasia mutant kinase (ATM) promoted macrophage recruitment in CRPC cells in vitro via C-X-C motif chemokine ligand 12.

[Molecular Biology Reports] Researchers aimed to clarify the regulatory roles of the SOX2/Notch axis in CRPC. They conducted immunohistochemistry analyses to evaluate SOX2, Notch, and Hey1 expression in the prostate cancer and CRPC tissues.

[Nature] Scientists found that down-regulation of the conserved cholinergic enzyme Acetylcholinesterase4 in the gut epithelium enables acetylcholine from specific TNF/Egr5-sensing cholinergic neurons to activate nicotinic receptors in innervated enterocytes.