Review

[Bone Research] Scientists provide a comprehensive overview of current research on the generation and coordination of skeletal interoceptive signals by the central nervous system to maintain bone homeostasis and their potential role in pathological conditions.

[Heliyon] Investigators highlight different strategies for generating human cardiac organoids using hPSCs while also critically discussing their challenges and limitations.

[Nature Reviews Bioengineering] Investigators contextualize the needs for predictive non-clinical models of human immune responses and we overview recent advances in bioengineering models of lymphoid tissues and immune-competent non-lymphoid tissues.

[Seminars In Cell & Developmental Biology] The increasing use and refinement of transgenic mouse models has played an instrumental role in offering new insights into the cellular origins of the coronary vasculature, as well as identifying a continuum of transitioning cell states preceding the full maturation of the coronary vasculature.

[Skin Pharmacology And Physiology] Investigators present a brief retrospective of the emergence of keratinocyte-based culture techniques. They also present opportunities and eventual problems that researchers might encounter when exploring the skin using such procedures.

[Cell And Tissue Research] The rate of progression and breakthrough in the area of in vitro spermatogenesis is lower than that of spermatogonial stem cell transplantation, but newer methods are being developed.