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Cytokines and Exosomal miRNAs in Skeletal Muscle–Adipose Crosstalk

[Trends In Endocrinology And Metabolism] Skeletal muscle and adipose tissues are secretory organs that release secretory factors including cytokines and exosomes. These factors mediate muscle–adipose crosstalk to regulate systemic metabolism via paracrine and endocrine pathways.

Thrown for a Loop: Fibro-Adipogenic Progenitors in Skeletal Muscle Fibrosis

[American Journal Of Physiology-Cell Physiology] The authors summarize fibro-adipogenic progenitors' role in fibrosis in terms of their activation, heterogeneity, contributions to fibrotic degeneration, and role across musculoskeletal diseases.

Red Blood Cells: A Potential Delivery System

[Journal Of Nanobiotechnology] The authors compared the various physiological and physical characteristics of RBCs, analyzed their potential advantages in delivery systems, and summarized their existing practices in biomedicine.

Alpha-Melanocyte Stimulating Hormone (α-MSH): Biology, Clinical Relevance, and Implication in Melanoma

[Journal of Translational Medicine] The authors explore the molecular biology of α-MSH with particular emphasis into its tumor-related properties whilst elaborating the experimental evidence on the interplay between α-MSH/melanocortin 1 receptor axis, melanoma, and antitumor strategies.

Who Wins the Combat, CAR or TCR?

[Signal Transduction And Targeted Therapy] The authors enumerate the mechanisms of immune checkpoint targets, associations between Immune-checkpoint inhibitors (ICBs) with tumour mutation burden, key immune regulatory or resistance signaling pathways, the specific clinical evidence of the efficacy of classical targets and new targets among different tumour types and put forward dialectical thoughts on drug safety.

Repurposing of Antiangiogenic Agents for Treatment of Vascular Anomalies

[Pharmacology & Therapeutics] The authors review the literature for conventional medications and products from traditional medicine cultures that have been found to have antiangiogenic activity.

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