Review

[Human Gene Therapy] Regulatory T cells are crucial for maintaining tolerance against self or nonself antigens. Of importance, Tregs also play an important role in dampening immune responses to AAV gene therapy, including tolerance induction to the transgene product.

[Heliyon] The authors provide an overview of the new advances of CAR-T cells in the cure of multiple myeloma (MM), so in this review we looked at the progress of the clinical use of CAR-T cells in MM to try to provide a reference for their clinical use when managing MM.

[Cell Death & Differentiation] Investigators described how regulated cell death modalities functionally affect epidermal SC niches along with their relevance to injury repair, inflammatory skin disorders and cancer.

[Heliyon] Scientists examine the properties and applications of nanoliposomes used in the treatment and prevention of numerous types of skin cancer.

[Respiratory Research] The authors highlight the more significant mediators of IRI-induced endothelial dysfunction discovered over the past decade including the extracellular glycocalyx, endothelial ion channels, purinergic receptors, kinases, and integrins.

[Cellular Reprogramming] The authors discuss the role of canonical signaling pathways implicated in regulation of pluripotency and differentiation particularly in mouse and human ESCs.